Posion Spider Glands is a Tier 3 Rune crafting material. It is used to make Master Dragon Slaying-Rune, which when slotted into a weapon, inflicts +32 damage on each weapon strike against dragons. In order to make this you will need to have completed War Table Operation: Acquire the Arcanist. Poison Spider Glands drop from Corrupting Spiders in the Forbidden Oasis.
- Type: Rune Crafting Material
- Tier: Tier 3
- Location: Drops from Corrupting Spiders
- Makes: Master Dragon-Slaying Rune
- Materials Needed: 1 Blank Runestone & 6 Poison Spider Glands